"Genetic heterogeneity, even within the same patient, can push clinical decisions to depend on analysis at the single-cell level. … In just a couple of hours from start to finish, DNA from a single cell is amplified by the AmpliSpeed instrument and ready for standard RT-PCR analysis." The article is pubished in Clinical Lab Products http://www.clpmag.com/issues/articles/2008-10_1.asp

"We have developed a microfluidic chip-based qualitative assay for sensitive (10 RNA copies) detection of multiple transcripts in single cells. We determined the expression patterns of 17 developmentally important genes and isoforms in individual mouse preimplantation embryos from superovulated matings and blastomeres."

In their product focus Nature is highlighting our CellEvator as one of the „Hottest new technologies“. Designed for the BD FACSAriaTM  CellEvator prevents cells settling and adhesion mixing vertically without the creation of air-bubbles. Inducing surface acoustic waves into the sample the CellEvator operates non-invasive and without any moving parts therefore being virtually maintenance free.

"Advalytix’ AmpliGrid technology is playing a key role in enabling researchers to discover how just a single cell can lay a huge role in complex biological systems."

"Tumor cells escape. In fact, scientists learned long ago — as early as 1869 — that cancer cells can end up in the blood. By the mid-1950s, some researchers thought that these so-called circulating tumor cells (CTCs) might help clinicians catch cancer earlier or measure the efficacy of a treatment." This story first appeared in the July 2008 issue of Bioscience Technology www.biosciencetechnology.com.

"The analysis of copy numbers of genetic sequences is of fundamental importance in biology and medicine, and Digital Counting (DigC) is a new method to determine copy numbers at the single-cell level. Researchers at Olympus’ Advalytix division have applied DigC to detect Trisomy 21 (Down syndrome) from single human fibroblasts."

"Despite general awareness of the significance of microplate mixing, it is still a relatively low priority in most laboratories. Microplate mixing has largely been ignored as a serious problem, although potentially it could undermine the generation of meaningful data."